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Index > Protein center > LNX1(Gene name) > Human
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  • LNX1 (Gene name),
  • E3 ubiquitin-protein ligase LNX (Protein name ),  LNX1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LNX1(UNQ574/PRO1136;UNQ574/PRO1136;LNX;PDZRN2);
    Protein name:
    E3 ubiquitin-protein ligase LNX;
    Alternative:
    Numb-binding protein 1;Ligand of Numb-protein X 1;PDZ domain-containing RING finger protein 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the phosphotyrosine interaction domain of all isoforms of NUMB (By similarity). Interacts with the Coxsackievirus and adenovirus receptor CXADR. Interacts with endogenous retrovirus K protein Np9. IGSF5/JAM4 interacts with isoform 2 through the second PDZ domain, other isoforms may also interact with IGSF5/JAM4.
    Function:
    Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    728
    Sequence:
    50:
    MNQPESANDP | EPLCAVCGQA | HSLEENHFYS | YPEEVDDDLI | CHICLQALLD | 
    100:
    PLDTPCGHTY | CTLCLTNFLV | EKDFCPMDRK | PLVLQHCKKS | SILVNKLLNK | 
    150:
    LLVTCPFREH | CTQVLQRCDL | EHHFQTSCKG | ASHYGLTKDR | KRRSQDGCPD | 
    200:
    GCASLTATAP | SPEVSAAATI | SLMTDEPGLD | NPAYVSSAED | GQPAISPVDS | 
    250:
    GRSNRTRARP | FERSTIRSRS | FKKINRALSV | LRRTKSGSAV | ANHADQGREN | 
    300:
    SENTTAPEVF | PRLYHLIPDG | EITSIKINRV | DPSESLSIRL | VGGSETPLVH | 
    350:
    IIIQHIYRDG | VIARDGRLLP | GDIILKVNGM | DISNVPHNYA | VRLLRQPCQV | 
    400:
    LWLTVMREQK | FRSRNNGQAP | DAYRPRDDSF | HVILNKSSPE | EQLGIKLVRK | 
    450:
    VDEPGVFIFN | VLDGGVAYRH | GQLEENDRVL | AINGHDLRYG | SPESAAHLIQ | 
    500:
    ASERRVHLVV | SRQVRQRSPD | IFQEAGWNSN | GSWSPGPGER | SNTPKPLHPT | 
    550:
    ITCHEKVVNI | QKDPGESLGM | TVAGGASHRE | WDLPIYVISV | EPGGVISRDG | 
    600:
    RIKTGDILLN | VDGVELTEVS | RSEAVALLKR | TSSSIVLKAL | EVKEYEPQED | 
    650:
    CSSPAALDSN | HNMAPPSDWS | PSWVMWLELP | RCLYNCKDIV | LRRNTAGSLG | 
    700:
    FCIVGGYEEY | NGNKPFFIKS | IVEGTPAYND | GRIRCGDILL | AVNGRSTSGM | 
    728:
    IHACLARLLK | ELKGRITLTI | VSWPGTFL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    String:
    UniGene:
    KEGG:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    E13521h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    E13521m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    U13521h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    U13521m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    P13521Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase LNX
    Cat.:
    P13521Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase LNX
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase LNX
    Protein for Human E3 ubiquitin-protein ligase LNX
    Protein for Human E3 ubiquitin-protein ligase LNX

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of a human LNX protein containing multiple PDZ domains."
      Xie Y. , Zhao W. , Wang W. , Zhao S. , Tang R. , Ying K. , Zhou Z. , Mao Y.
      Biochem. Genet.39:117-126(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
      tissue: Fetal brain.
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Prostate.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Placenta.
    6. 6.
      "The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX)."
      Sollerbrant K. , Raschperger E. , Mirza M. , Engstroem U. , Philipson L. , Ljungdahl P.O. , Pettersson R.F.
      J. Biol. Chem.278:7439-7444(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CXADR
    7. 7.
      "Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X."
      Armbruester V. , Sauter M. , Roemer K. , Best B. , Hahn S. , Nty A. , Schmid A. , Philipp S. , Mueller A. , Mueller-Lantzsch N.
      J. Virol.78:10310-10319(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NP9
    8. 8.
      "MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases."
      Doyle J.M. , Gao J. , Wang J. , Yang M. , Potts P.R.
      Mol. Cell39:963-974(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAGEB18 AND MAGEF1
    9. 9.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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